Best ADC and Support Synergies in League of Legends (2025 Practical Guide)

November 18, 2025
This guide was created by STATUP.GG, an AI-powered voice coach designed to help you play smarter and more confidently.

Bot lane synergy is one of the most important factors in League of Legends. Even when playing the same ADC, your early pressure, skirmish success rate, and late game carry potential can vary greatly depending on which support you lane with.

This guide focuses on which supports pair well with each ADC. Rather than simply listing counter matchups, it analyzes each champion’s skill mechanics and their points of synergy so you can apply them directly in real games.

Caitlyn

A champion that needs to gain advantages in the laning phase. She must push the wave quickly to maximize her strengths.

  • Lux: Fast wave clear. Lux Q can combo with Caitlyn W.
  • Morgana: Fast wave clear. Morgana Q can combo with Caitlyn W.

Jhin

A champion that needs to gain advantages during the laning phase. He has strong synergy with supports who can push the wave and apply long range poke.

  • Xerath, Karma, Vel'Koz: Long range poke that works well with Jhin W follow-up.
  • Leona: Every long range engage skill she has can be followed by Jhin W.

Jinx

Weak in lane but a strong late-game carry. She works well with champions who can protect her or set up her abilities since she has no mobility.

  • Thresh: Protects Jinx with W and E. Thresh Q can combo with Jinx E.
  • Lulu: Protects and buffs Jinx with W, E, and R. Very strong scaling value.

Ashe

Her basic attacks apply a slow, so she works well with champions who can follow up on that effect.

  • Seraphine: Can root immediately with her E.
  • Senna: Applies a slow with her Q. Both champions can use the rune Approach Velocity effectively.
  • Braum: Strong kiting synergy with his passive and E.

Kai'Sa

Her passive gains stacks whenever an ally lands crowd control, and at four stacks it deals bonus damage. She works best with supports who can reliably trigger those stacks.

  • Nautilus: Passive, Q, R
  • Rell: W, Q, R
  • Leona: Q, E, R
  • Maokai: Q, W, R

Lucian

His passive has two effects, and he works best with supports who help him use both of them: firing two shots after using an ability, and dealing bonus damage when hitting a crowd-controlled target.

  • Nami, Braum: Great synergy with his passive that lets him fire two shots after casting an ability.
  • Nautilus, Rell, Leona, Maokai: Crowd control hits that allow Lucian to trigger the bonus damage portion of his passive.

Miss Fortune

She works well with champions who can set up her ultimate ability after level 6.

  • Nautilus, Leona, Maokai: Their long-range crowd control sets up her ultimate.

Ezreal

He is strongest when he can land his Q on champions rather than minions, so he has good synergy with supports who can help push the wave.

  • Karma: Can push the wave and poke together with Ezreal.
  • Bard: Ezreal can farm safely on his own thanks to his mobility, which allows Bard to roam freely.

Samira

She synergizes with champions who can maximize all three parts of her passive: her style rank system, bonus melee damage, and her dash plus airborne follow-up on crowd control hits.

  • Nautilus, Rell, Alistar: All provide airborne effects.

Draven

He has a strong laning phase and a passive that grants bonus gold, so he pairs well with champions who excel at securing kills.

  • Pyke: Pyke’s ultimate can also trigger Draven’s passive.
  • Blitzcrank: Can force fights with Q grabs or Flash E.

Tristana

Her E stacks are key, and she works well with champions who can force engages or help her go in with her W.

  • Rakan, Yuumi: Can engage together with Tristana’s engage and help force fights.

Vayne

She is very weak in lane but works well with supports who can help her fight effectively after level 6.

  • Braum: Can follow Vayne’s Q engage once she reaches level 6.
  • Lulu: Enhances Vayne’s basic attacks and provides strong protection.

Aphelios

A hard-carry ADC with no mobility. He works best with champions who can provide protection and maximize his damage output.

  • Lulu: W buff and R protection.
  • Thresh: W for protection and good synergy with Aphelios’s root and Q combinations.

Twitch

He works well with champions who can enhance his instant engage when he emerges from stealth..

  • Rakan, Yuumi: Strong follow-up and engage after Twitch leaves stealth.
  • Lulu: W buff and R protection.

Corki

His full-hit E deals heavy damage but has short range. He works well with champions who can help him land the full damage with crowd control.

  • Rakan: Can accompany Corki’s W engage.
  • Leona, Nautilus: Their long-lasting crowd control helps Corki land full-hit E.

Zeri

A weak laner but a strong late-game carry. She works well with champions who provide strong protection and buffs.

  • Lulu, Yuumi: Provide buffs and protection with their W, E, and R.
  • Rakan: Helps with engage and peel.

Sivir

She can push the wave quickly and poke, so she works well with champions who can apply lane pressure together with her.

  • Karma, Yuumi: Enable long-range wave clear and poke together.

Kog'Maw

A champion whose key timing is the eight seconds when his W is active. He works best with champions who provide buffs and survival support.

  • Lulu: Lulu: Uses her W and R during Kog’Maw’s W to maximize both his damage buffs and his survivability
  • Braum: Offers protection with his E.

Xayah

She synergizes with champions who can set up crowd control that works with her feathers.

  • Rakan: Shares recall, provides a movement speed bonus through Xayah’s W, and enables CC follow-up.
  • Nautilus, Rell, Leona: Their crowd control works well with the root from Xayah’s E.

Kalista

She has a strong laning phase and pairs well with champions who can help her maximize her ultimate.

  • Renata Glasc: Able to provide mutual protection with Kalista through her ultimate and W.
  • Pyke: Maximizes lane pressure.
  • Thresh: As a ranged champion, he helps maximize the bonus damage from Kalista’s W passive (the Oathsworn’s basic attacks), providing lane pressure and protection.

 jNilah

She has two passive effects increased experience gain and amplified healing and shielding. She synergizes with champions who can maximize these effects.

  • Yuumi, Rakan: Enhance her passive effects and assist her in using her E effectively.

Ziggs

He works well with champions who can compensate for the limitations of his non-targeted abilities.

  • Leona, Nautilus, Rell: Their strong crowd control helps Ziggs land his non-targeted skills.
  • Bard: Ziggs’s wave clear allows Bard to roam more freely.

Varus

He can be played in both a basic-attack style and a poke style, and he has low dependence on supports.

  • Basic-attack style: Lulu and Thresh, who provide basic attack enhancement and survival support.
  • Poke style: Xerath and Karma, who provide poke and wave-clear support.

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